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public static extern int RegFlushKey(IntPtr hKey);

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   Declare Function RegFlushKey Lib "CoreDll.dll" (ByVal hkey As IntPtr) As UInt32

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   Declare Function RegFlushKey Lib "coredll" (ByVal hkey As IntPtr) As UInt32

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   RegFlushKey(HKEY_CLASSES_ROOT)

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   RegFlushKey(HKEY_CURRENT_USER)

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   RegFlushKey(HKEY_LOCAL_MACHINE)

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   RegFlushKey(HKEY_USERS)

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Documentation

[RegFlushKey] on MSDN